GP Clomiphene is a medication commonly used in women for the treatment of infertility. It is often used to induce ovulation in women that do not develop and release an egg (ovulate) on their own. GP Clomiphene is also used to stimulate extra follicles and eggs in the ovaries of women that already ovulate without medications.
Male bodybuilders who cycle anabolic androgenic steroids (AAS) have found that the same mechanisms of increased LH (luteinizing hormone) can be taken advantage of to increase total testosterone levels. This is why GP Clomiphene is popular in post cycle therapy (PCT) among those who cycle anabolic steroids. Since GP Clomiphene has ability to bind to the estrogen receptors, much like nolvadex, in male users who run estrogenic compounds such as testosterone, dianabol, and deca durabolin, it can be used as gynecomastia treatment (anti-gyno). However, GP Clomiphene is a fairly weak anti-gyno aid, and is rarely used for that purpose. Due to its ability to boost testosterone levels, it has been put on the WADA (world anti-doping agency) list of illegal doping agents in sport.
GP Clomiphene is available in 50 mg tablets. Treatment of the selected patient should begin with a low dose, 50 mg daily (1 tablet) for 5 days; dose changes are made by the treating physician. The first dose should occur on the 5th day of the female’s ovulatory cycle and then subsequent doses at about the same time of day for a total of 5 days. Patients should be familiar with their ovulatory cycle so that properly timed coitus and ovulation stimulated by the drug occur. Long term therapy (past 6 cycles) is not recommended to avoid possible increases in cancer risk. Serious side effects of GP Clomiphene include shortness of breath, seizures, stroke, chest pain, vision changes, GI symptoms of pain and swelling. Ovarian hyperstimulation syndrome may occur (ovarian enlargement, severe GI symptoms, abdominal swelling, shortness of breath, pleural effusions, decreased urination). Patients should seek medical care if these serious symptoms develop. This drug is not for use in males or pediatric patients; studies on its excretion in breast milk have not been done.
Use caution when driving, operating machinery, or performing other hazardous activities. Clomiphene may cause blurred vision or other visual side effects during or shortly after therapy. Notify your doctor immediately if you develop any visual side effects and use caution when performing hazardous activities, especially under conditions of variable lighting.
Clomiphene may increase the likelihood of multiple births. Multiple births may carry additional risk both for the mother and for the fetuses.