Aromadex is a powerful steroid estrogen suppressor developed, produced and marketed by Sciroxx. The pills are used by athletes and bodybuilders taking other steroids and desiring to avoid estrogen related side effects. Additionally Aromadex (Exemestane) will increase the level of testosterone and IGF. The drug can be used in any cycles. It is also recommended for post cycle therapy.
Aromadex averages an 85% rate of estrogen suppression, so it’s clearly a very effective agent for bodybuilders and other athletes wanting to avoid estrogen related side effects such as gyno, acne, or water-retention brought on by aromatizing steroids. Specifically, Aromadex dose this by selectively inhibiting aromatase activity in a time-dependent and irreversible manner.
As with most of the compounds in this class, it also causes a reasonable rise in testosterone levels, and as you may have guessed, this rise in testosterone means that Aromadex can also cause androgenic sides. As you can see from the chart below, exemestane is very effective at both lowering estrogen (estradiol) and raising testosterone: Estrogen and androgen plasma levels after 10 d of daily exemestane (25 or 50 mg) in healthy young males. To convert to Systeme International units: estradiol, picomoles per liter; estrone, picomoles per liter; androstenedione, nanomoles per liter; and testosterone, nanomoles per liter.
So we can see that 25 mgs is a very effective dose from that chart, right? As an added benefit, exemestane not only increases testosterone and lowers estrogen, but it also increases IGF levels. Additionally Worth noting is that Aromadex may possibly be less harsh on blood lipids than some of the other (similar) compounds we use in the world of bodybuilding or athletics. It also has, at best no effect on IGF, and at worst could lower it. AI’s are very tricky with regards to inconsistencies in IGF levels.
Note that anti aromatases (Aromasin, Femara, Arimidex) are often confused with anti estrogens (Nolvadex). Anti aromatases work quite differently than anti estrogens do. Anti estrogens are actually weak estrogens that attach to the estrogen receptor sites in the body (such as the nipple and breast area), by doing so they block the ‘bad’ estrogens from attaching to these sites. Anti aromatases on the other hand block the formation of estrogen in the body in the first place. They do this, by blocking the enzyme aromatase which is responsible for the conversion of testosterone to estrogen, so there is less estrogen circulating in the blood. In a sense, an anti aromatase such as Aromasin takes care of the problem right from it’s root.